An International Publications House

Albert Science International Organization

Connecting People With Pioneering Thought

Albert Science International Organization (ASIO) is international , peer-reviewed , open access , cum print version & online journals.
JOURNALS || ASIO Journal of Pharmaceutical & Herbal Medicines Research (ASIO-JPHMR) [ISSN: 2455-281X]
IMPORTANCE OF BIOENGINEERING IN PHARMACY

Author Names : Subarna Mahanti
Page No. : 07-13
Read Hit : 1101
Pdf Downloads Hit : 34  Volume 6 Issue 1
Article Overview

ARTICLE DESCRIPTION: 

Subarna Mahanti, Dr. Dhrubo Jyoti Sen, Dr. Bankim Chandra Nandy, Dr. Falguni Patra, Dr. Khokan Bera and Dr. Beduin MahantiIMPORTANCE OF BIOENGINEERING IN PHARMACY, ASIO Journal of Pharmaceutical & Herbal Medicines Research (ASIO-JPHMR), 6(1), 2020: 07-13.

ARTICLE TYPE: Review

DOI Link :: http://doi-ds.org/doilink/10.2016-19146535/ ; DOI Link :: http://doi-ds.org/doilink/05.2020-44963474/


ABSTRACT:

Biomedical engineering, or bioengineering, is the application of engineering principles to the fields of biology and health care. Bioengineers work with doctors, therapists and researchers to develop systems, equipment and devices in order to solve clinical problems. Examples of bioengineering research include bacteria engineered to produce chemicals, new medical imaging technology, portable and rapid disease diagnostic devices, prosthetics, biopharmaceuticals, and tissue-engineered organs.

KEYWORDS: Bioengineering, Drug discovery, Bioengineered Therapeutics, Importance of Sugar, In-vitro processes, 3D bioprinting, Organ-on-chip, Biosensors, Microtissue, Medical devices.

Reference

1. Duval K, Grover H, Han L-H, et al. Modeling physiological events in 2D vs. 3D cell culture. Physiology. 2017; 32: 423–450.

2. Kimura H, Sakai Y, Fujii T. Organ/body-on-a-chip based on microfluidic technology for drug discovery. Drug Metab Pharmacokinet. 2018; 33: 43–48.

3. Kacy Cullen D, Wolf JA, Vernekar VN, et al. Neural tissue engineering and biohybridized microsystems for neurobiological investigation in vitro (part 1). Crit Rev Biomed Eng. 2011; 39: 201–240.

4. Lee SH, Sung JH. Organ-on-a-chip technology for reproducing multiorgan physiology. Adv Healthcare Mater. 2018; 7: 1700419.

5. Yamada KM, Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell. 2007; 130: Cell, 2007, 130(4):601-10.

6. Hoarau-Véchot J, Rafii A, Touboul C, et al. Halfway between 2D and animal models: are 3D cultures the ideal tool to study cancer-microenvironment interactions? IJMS. 2018; 19: 181.

7. Edmondson R, Broglie JJ, Adcock AF, et al. Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors. Assay Drug Dev Technol. 2014; 12: 207–218.

8. Shanti A, Teo J, Stefanini C. In vitro immune organs-on-chip for drug development: a review. Pharmaceutics. 2018; 10: 278.

9. Ericsson AC, Crim MJ, Franklin CL. A brief history of animal modeling. Mo Med. 2013; 110: 201–205.

10. Seok J, Warren HS, Cuenca AG, et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Natl Acad Sci. 2013; 110: 3507–3512.

11. Polini A, Del Mercato LL, Barra A, et al. Towards the development of human immune-system-on-a-chip platforms. Drug Discov Today. 2018; 24: 1–9.

12. Rossi G, Manfrin A, Lutolf MP. Progress and potential in organoid research. Nat Rev Genet. 2018; 19: 1–17.

13. Mehta HS, Bhatt NA and Sen DJ; Enteroclysis and computed tomographic enterography in medical imaging: European Journal of Pharmaceutical and Medical Research. 2015; 2(3): 691-705.

14. Sato T, Vries RG, Snippert HJ, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature. 2009; 459: 262–265.

15. Eiraku M, Takata N, Ishibashi H, et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature. 2011; 472: 51–56.

16. Lancaster MA, Renner M, Martin C-A, et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013; 501: 373–379.

17. Takahashi T. Organoids for drug discovery and personalized medicine. Ann Rev Pharmacol Toxicol. 2019; 59: 447–462.

18. Fang Y, Eglen RM. Three-dimensional cell cultures in drug discovery and Development. SLAS Discov. 2017; 22: 456–472.

19. Parmar AM, Patel KD, Doshi ND, Kapadiya GM, Patel BS and Sen DJ; Correlation approach between shotgun sequencing with DNA sequencing in molecular genomics: World Journal of Pharmacy and Pharmaceutical Sciences: 2014; 3(11): 963-995.

20. Pasotti, Lorenzo; Zucca, Susanna. "Advances and Computational Tools towards Predictable Design in Biological Engineering". Computational and Mathematical Methods in Medicine. 2014: 369681. 2014; 2014: 369681.

21. Kapadiya GM, Parmar AM and Sen DJ; Western blotting: an unique technology for detection of proteins by antigen-antibody interaction: World Journal of Pharmacy and Pharmaceutical Sciences: 2014; 3(10): 1810-1824.