Albert Science International Organization

ARTICLE DESCRIPTION: 

Akash Babu, Abhishek Singh, Formulation and evaluation of vasaka traditional medicine based herbal lozenges,  ASIO Journal of Drug Delivery (ASIO-JDD), 2020, 4(1): 11-15.

ARTICLE TYPE: RESEARCH

Affiliation: Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly-243202, (U.P.), India

DOI Link:: 10.2016-21915953/ ;

DOI Link :: http://doi-ds.org/doilink/07.2020-57551629/

ABSTRACT:

Development of lozenges dating back to the 20th century and is still popular among consumers, and has therefore continued to produce commercially. Lozenges are administered in the oral cavity as a palatable solid unit dosing form. For its local or systemic effect they meant being dissolved in the mouth or pharynx. Lozenge tablets however offer several advantages with some disadvantages as pharmaceutical formulations. Lozenge as a dosage form can be adopted through buccal route, labial route, gingival route, and sublingual route for drug delivery. Multiple drugs for chronic illness treatments can also be incorporated into them. Lozenge allows for the loading of a wide range of active ingredients for the oral systemic drug delivery. Lozenges are available in the form of soft lozenges based on caramel, hard candy lozenges and compressed tablet lozenges containing drugs for sore throat, mouth infection and as mouth fresheners over the counter medications. The reasoning behind using medicated lozenges as one of the most preferred dosage type for antitussive drug delivery. This review focuses on various aspects of lozenge formulation providing an insight into the novel application of the lozenge drug delivery system to the formulating scientist.

Keywords: Vasaka lozenges, expectorants, buccal route, labial route, gingival route, and sublingual route for drug delivery.

1. British pharmacopoeia, volume ?, 9th edition, 2018, ?63.
2. Umashankar M.S., Dinesh S.R., Rini R., Lakshmi K.S., Chewable lozenge formulation-A   Review , International Research Journal of Pharmacy; 2016, 7(4), 9-16.
3. Stephen O. Majekodunmi, A Review on Lozenges, American Journal of Medicine and Medical Research, 2015, 5(2), 99-104.
4. Renuka P., Madhusudan Y., Lozenges Formulation and Evaluation- A Review, International Journal of Advances in Pharmaceutical Research, 2014, 5(5), 290- 298.
5. Surbhi C., Review on Lozenges for Oral Bacterial Infection, International Journal of Pharmacy, 2017, 7(1), 16-22.
6. Tania S., Tejasavi M., Suxam, Sunil K., Sonia P., Neeraj B., Medicated Lozenges –A Review, World Journal of Pharmacy and Pharmaceutical sciences, 2018, 7(10), 751-756.
7. Minakshi R., Sachin P., Yuvraj P., Monali M, Sudesh S., Medicated lozenges as an easy to use dosage form, World Journal of Pharmaceutical Research, 2018,7(16), 305-322.
8. Raymond C Rowe, Paul J Sheskey and Marian E Quinn. Handbook of Pharmaceutical excipients. Pharmaceutical press. Ed 6; 94-96, 181,404,441, 596, 686, 701.
9. https://www.wikihow.com/Extract-Ginger-Juice
10. https://sg.inflibnet.ac.in/bitstream/10603/25072/8/08_chapter%204.pdf
11. The Pharmaceutics & Compounding Laboratories at the UNC Eshelman School of Pharmacy. [Cited 2015 December 29]; [about 1p.].
12. Mohan H. Text book of Pathology – The oral cavity and salivary glands. 4th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2000: 494-496.
13. J F Firriolo. Oral cavity- A Review. Oral Surg Med Oral Pathol. 1994; 78(2): 189-193.
14. The Pharmaceutics and compounding Laboratory, Lozenges and medication sticks. [Cited 2015 December 29]; [about 3p.]. 
15. Deepak R, Sanjay S. Formulation and evaluation of antianthalmentic Chewable tablet. Int Pharma Sciencia. 2012; 2(1): 13-26.
16. Bhatti A, Singh T. Preparation of tablets rapidly disintegrating in saliva containing bitter taste-masked granules by compression method. Indian Journal of Pharmaceutical Sciences 2007; 69(1):80.
17. Pharmacopoeia US. 30/NF25. US Pharmacopoeial Convention, Rockville, MD 2013 May (Vol. 1691).
18. Pharmacopoeia British. Version 11.0. Appendices: XII A, XII G, XVII G. 2013.