Albert Science International Organization

ARTICLE DESCRIPTION: 

Affiliation:

Department of Pharmacy, Navsahyadri Institute of Pharmacy, Naigaon (Nasarapur), Pune, India.

ARTICLE TYPE: REVIEW

DOI : 10.2016-19146535/ ; DOI Link :: http://doi-ds.org/doilink/11.2020-88179158/

ABSTRACT:

Momordica charantia (bitter gourd; family Cucurbitaceae) is a crucial medicative vegetable crop, mostly found in tropical and climatic zone regions of Asia, tropical continent, geographical region and America. Bitter melon has been used as a folks remedy for tumors, asthma, skin infections and high blood pressure. The plant hasbeen used as a conventional drug in China, India, Africa, and therefore the south-eastern United States of America. it's a nonnitrogenous neutral principle charantin, and on chemical reaction offers aldohexose and a steroid alcohol. The fruit pulp has soluble cellulose however no free acid. Galacturonic acid is additionally obtained from the flesh. Bitter gourd is rich in nutrients like B, carotin, folate, riboflavin, and minerals like metal, iron, phosphorus, manganese, potassium, magnesium, metal and dietary fiber. Regular use of bitter gourd juice boosts body stamina and prevents chronic fatigue. The carotin content in bitter gourd helps in controlling eye disorders and enhances sight. Bitter melon has anti-Tumor, anti-inflammatory drug, Inhibitor action, hypo-lipidemic, hypo-glycaemic properties etc. 

Key Words-Momordica charantia, medicinal properties, pharmacology, Chemical Compostion, Phytochemical constutients.

1. Botanical Society of Britain and Ireland. Archived from the original (xls) on 2014-10-23. Retrieved 2014-10-17.
2. Bagchi, Indrani (11 April 2005). "Food for thought: Green 'karela' for Red China". Times of India.
3. https://en.wikipedia.org/wiki/Momordica_charantia
4. https://www.researchgate.net/figure/Bitter-gourd-fruit-type-variation-Photos-courtesy-of-Ms-Supunsa-Phethin_fig6_267342805
5.  Ee Shian T, Aminah A, Nur Kartinee K, Shahrul Hisham ZA. Antioxidant and hypoglycaemic effects of local bitter gourd fruit (Momordica charantia). International Journal of pharm Tech Research. 2015; 8(1):46-52
6. https://www.researchgate.net/figure/Fruits-of-different-variety-of-Momordica-charantia-available-in-Bangladesh-Upper-left_fig2_269166311.
7. Kumar DS, Sharathnath KV, Yogeswaran P, Harani A, Sudhakar K, Sudha P et al. A medicinal potency of Momordica charantia. International Journal of Pharmaceutical Science Review Research. 2010; 1(2):95.
8. https://www.lybrate.com/topic/benefits-of-bitter-melon-and-its-side-effects
9. Ganesan A, Natesan S, Perumal PG, Vellayutham R, Manickam K, Ramasamy N. Anxiolytic, antidepressant and anti-Inflammatory activities of methanol extract of Momordica charantia Linn Leaves (Cucurbitaceae). International Journal of Pharmacy and Technology. 2008; 7(1):43-47
10. Anilakumar KR, Kumar GP, Ilaiyaraja N. Nutritional, pharmacological and medicinal properties of Momordica charantia. International Journal of Nutrition and Food Sciences. 2015; 4(1):75-83
11. https://www.frontiersin.org/articles/10.3389/fphar.2019.00486/full.
12. Ganesan A, Natesan S, Perumal PG, Vellayutham R, Manickam K, Ramasamy N. Anxiolytic, antidepressant and anti-Inflammatory activities of methanol extract of Momordica charantia Linn Leaves (Cucurbitaceae). International Journal of Pharmacy and Technology. 2008; 7(1):43-4.
13. Sharma R. Medicinal plants of India- an Encyclopedia. Daya Publishing House, Delhi. 2003, 160-161.
14. https://www.mdpi.com/2072-6694/12/8/2064/htm
15. Zimmet P, Shaw J, Alberti KGMM. Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: a realistic view Diabet Med, Sep. 2003; 20(9): 693–702.
16. Gupta AK, Tandan N, Sharma N. Quality Standards of Indian Medicinal Plants, ICMR. 2005, 3:262-270.
17.  Indian Medicinal Plants. A Compendium of 500 species, Orient Longman Ltd., Madras 1995; 4: 48-51.
18. http://www.gmanews.tv/story/35962/Ampalaya-tablets- out-soon-for-diabetics
19. Horax R, Hettiarachchy N and Islam S: Total Phenolic contents and phenolic acid constituents in four varieties of bitter melons (Momordica charantia) and antioxidant activities of their extracts. J Food Sci. 2005; 70.
20.  Sathishsekar D and Subramanian S: Antioxidant properties of Momordica Charantia (bitter gourd) seeds on Streptozotocin induced diabetic rats. Asian Pacific J Clin Nutr. 2005; 14(2):153-158.
21. Dhar, P., S. Ghosh and D.K. Bhattacharyya, Dietary effects of conjugated octadecatrienoic fatty acid (9 cis, 11 trans, 13 trans) levels on blood lipids and nonenzymatic In vitro lipid peroxidation in rats. Lipids. 1999; 34: 109-114.
22. Cunnick, J.E., K. Sakamoto, S.K. Chapes, G.W. Fortner and D.J. Takemoio,. Induction of tumor cytotoxic immune cells using a protein from the bitter melon (Momordica charantia). Cell. Immunol. 1990; 126: 278-289.
23. Kumar DS, Sharathnath KV, Yogeswaran P, Harani A, Sudhakar K, Sudha P et al. A medicinal potency of Momordica charantia. International Journal of Pharmaceutical Science Review Research. 2010; 1(2):95.
24. Head KA. Herbal remedies that may help control blood sugar.In: Bratman S, Kroll D. The Natural Pharmacist, Everything You Need to Know About Diabetes. New York, NY: Prima Publications, Inc. 1999, 53-58.