Albert Science International Organization

ARTICLE DESCRIPTION: 

Affiliation:

^1-6Students of School of Pharmacy, Techno India University, Kolkata, West Bengal, India.

⁷Associate Professor, Department of Pharmaceutics, School of Pharmacy, Techno India University, Kolkata, W.B., India.

ARTICLE TYPE: REVIEW

DOI : 10.2016-19146535/ ; 

DOI Link :: http://doi-ds.org/doilink/06.2021-65648722/ASIO-JPHMR: 2021/456

Abstract:

Polymeric nanoparticles (PNPs) are defined as particulate dispersion or solid particles with the size in the range of 10-1000nm.In present time nanoparticles are widely used in many dosage forms due to their good solubility, less size and better penetrability. Nanoparticles can be prepared by using various methods such as Solvent evaporation, salting out, dialysis, and supercritical fluid technology. The choice of method depends on particle size, particle size distribution etc. Polymeric nanoparticles have been extensively studied as particulate carriers in the pharmaceutical and medical fields because they have controlled and sustained release properties. In this review the different techniques for preparation of polymeric nanoparticles are described.

Keywords: Polymeric nanoparticles, particulate carriers.

1. Dubchak S, Ogar A, Mietelski JW, Turnau K (2010) Influence of silver and titanium nanoparticles on Arbuscular mycorrhiza colonization and accumulation of radiocaesium in Helianthus anus. Span J Agric Res 8: 103-108.
2. Gayatri K, Lakshmi G, Preeti K, Sayantan M (2012) Nanoparticles: A novelistic approach for CNS disorders. J Adv Pharm Sci 2: 220-259.
3. Hagan SA, Coombes AGA, Garnett MC, Dunn SE, Davies MC (1996) Polylactide {poly (ethylene glycol)} copolymers as drug delivery systems Langmuir 12: 2153-2161.
4. Reverchon E, Adami R (2006) Nanomaterial and supercritical fluids. J Supercrit Fluids 37: 1-22.
5. Kreuter J. Nanoparticles. In: Kreuter J, editor.colloidal drug delivery systems, vol.66 NEW YORK: Marcel Dekkar; 1994, p.219-342.
6. Couvreur P. Poly alkyl cyanoacrylates as colloidal drug carriers. Crit Rev Ther Drug Carr syst 1988; 5:1-20.
7. Vauthier C, Couvreur P. Development of nanoparticles made of polysaccharides as novel drug carrier systems.in; Wise Dl,editor.Handbook of pharmaceutical controlled release technology. New York; Marcel Dekker; 2000. p. 13-429.
8. Couvreur P, Deburnet C,Puisieux F.Controlled drug delivery with nanoparticles: current possibilities and future trends.Eur j Pharm Biopharm 1995;41:2-13.
9. Abhilash M. Potential application of nanoparticles J Pharm Bio Sci 1(1) 2010.
10.  Kayser. O,A. Lemke and N. Hernandez- Trejo. (2005) The Impact of nanobiotechnology on the development of new drug delivery system. Current Pharmaceutical Biotechnology  6(1),35.
11. Nagavarma BVN, Hemant KS, Yadav Ayuz A, Vasudha LS, Shivakumar HG (2012) Different techniques for preparation of polymeric nanoparticles - A review. Asian J Pharm Clin Res 5: 1-8.
12. Joachim A (2013) Synthesis of organic and bioorganic nanoparticles: An overview of the preparation methods. Springer-Verlag: London, pp: 27-30.
13. Catarino Pinto Reis, Ronald J. Neufold, Antonio J. Ribeiro,, Francisco Veiga. Nanoencapsulation I. Methods for preparation of drug loaded polymeric nanoparticles Nanomedicine: Nanotechnology, Biology, and Medicine 2(2006)8-21.
14. Sovan LP, Utpal J, Manna PK, Mohanta GP, Manavalan R (2011) Nanoparticle: An overview of preparation and characterization J of App Pharm Sci 1:6:228-234.
15. Fessi H, Puisieux F, Devissaguet JP, Ammoury N , Benita S. Nano capsule formation by interfacial deposition following solvent displacement . Int JPharm 1989, 55; R1-R4.
16. Barichello JM, Morishita M, Takayama K,Nagai T.Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles and nanoprecipitation method. Drug Dev Ind Pharm 1999, 25; 471-6.
17. Galindo-Rodriguez S, Allemann e, Fessi H, Deolker E,Physiological parameters associated with nanoparticle formation in the salting out emulsification- diffusion and nanoprecipitation methods. Pharm Res 2004, 21:1428-39.
18. Spontaneous emulsification as an alternative to ultrasonic and high-shear devices. Chem Phys Chem 2005,6: 209-16.
19. Tamizhrasi S, Shukla A, Shivkumar T, Rathi V, Rathi JC (2009) Formulation and evaluation of Lamivudine loaded polymethacrylic acid nanoparticles. Int J Pharm Technol Res 1: 411-415.
20. Mohanraj VJ, Chen Y (2006) Nanoparticles - A review. Trop J Pharm Res 5: 561-573.
21. Saikat D, Rinti B, Jayesh B (2005) Aspirin loaded albumin nanoparticles by coacervation: Implications in drug delivery trends. Biomater Artif Organs 18: 1-10.
22.  https://images.app.goo.gl/9zmMaE6M5cojYzev7
23. Puglisi G, Fresta M, Giammona G, Ventura CA, Influence of the preparation condition on poly(ethylcyanoacrylate) Nano capsule formation, Int J Pharm, 1995;125:283-287.
24. Fessi H, Puisieux F, Devvisaguet JP, Ammoury N, Benita S, Nano capsule formation by interfacial deposition following solvent displacement, Int J Pharm, 1989, 55: R1-R4.
25. Chorney M, DA neuberg H, Golomb G, Lipophillic drug loaded nanospheres by nanoprecipitation: effect on formulation variables on size, drug recovery and released kinetics, J Control release, 2002; 83:389-400.
26. PrasadRao J, KurtE, Geckeler Polymer nanoparticles: Preparation techniques and size control parameters, Progress in Polymer Science G Model. J Pharm Pharmaceuti Sci-674.
27. https://images.app.goo.gl/F5jptZMFNuyn7FtB7
28. https://images.app.goo.gl/1c4BoitNzznSaoXi6