1Department of Biochemistry, Federal Polytechnic, Ekowe, Bayelsa State, Nigeria
2Department of Biotechnology, Federal University of Technology, Owerri, Imo State, Nigeria
3-5Department of Science Laboratory Technology, Federal Polytechnic, Ekowe, Bayelsa State, Nigeria
ARTICLE TYPE: RESEARCH
DOI : 10.2016-19146535/ ;
DOI Link :: https://doi-ds.org/doilink/06.2021-76274373/10.2016-19146535/ASIO-JPHMR/2021/457
Abstract:
It is estimated that about 80% of the world’s population use medicinal plants either in their crude form or partially in their modified semi-synthetic form for their medical care. The efficacy of these plants in curing diseases is believed to be as a result of active biochemical compounds present, these bioactive compounds vary in compositions and types. Garden egg also known as eggplant is one of such plants. This research was aimed at profiling the preliminary phytochemicals and antimicrobial potentials of white-green African garden egg (Solanum macrocarpon) fruits obtained from Yenagoa Nigeria. Qualitative and quantitative phytochemical analysis was done using the standard method of Association of Official Analytical Chemist and agar well diffusion method was employed for antimicrobial assay. Preliminary phytochemical profile shows that Flavonoid content (25.6±0.01%) was highest followed by Saponin (14.3±0.01%), alkaloid (4.4±0.01%), Tannin (2.9±0.01%), Steroid (2.5±0.02%) and Terpenoid (1.6±0.01%). The antimicrobial assay revealed that methanol extract was more sensitive to bacteria [Shigella spp (14.7±0.2 mm), Staphylococcus spp (13.1±0.3 mm) and E. coli (12.3±0.2 mm)] and fungi [Penicillium sp (6.3±0.3 mm)] isolates. While aqueous extracts were more sensitive to bacteria (Vibrio sp with 9.5±0.9 mm) and fungi [Yeast (6.3±0.6 mm) and Mould (9.8±1.5 mm)] isolates. In light of these findings, S. macrocarpon fruits obtained from Yenagoa, Bayelsa State, Nigeria, could be considered as a potential source of natural antimicrobial and could be of a great importance for the treatment of infectious diseases caused by the test organisms.
Keywords: Phytochemical profile, Antimicrobial, Extracts, Medicinal plants, Yenagoa.
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