An International Publications House
Albert Science International Organization
Connecting People With Pioneering Thought
Author Desk
Our Journals
JOURNALS || ASIO Journal of Medical & Health Sciences Research (ASIO-JMHSR)
Medication and treatment guideline compliance: Most important but mostly despised
Author Names : Abdul Kader Mohiuddin Page No. : 11-18
Read Hit : 737
Pdf Downloads Hit : 10 Volume 7 Issue 1
Article Overview
ARTICLE DESCRIPTION:
Abdul Kader Mohiuddin, Medication and treatment guideline compliance: Most important but mostly despised, ASIO Journal of Medical & Health Sciences Research (ASIO-JMHSR), 2023, 7(1): 11-18.
Alumnus, Faculty of Pharmacy, Dhaka University, Bangladesh
doi: 10.2016-74831794; DOI Link :: https://doi-ds.org/doilink/02.2023-43427952/ASIO-JMHSR/10.2016-74831794/V7/I1/238
ABSTRACT:
Introduction and aim: To cure any disease, proper use of medicine or taking medicine in the correct order is required. Even patients from developed countries struggle to maintain their drug compliance. There is an odd parallel between underdeveloped, emerging nations and the so-called developed world in the West when it comes to improper medicine use. The understanding and perception of the disease is the most important factor influencing whether patients stick to their treatment plan.
Material and methods: Non-systematic review.
Analysis of the literature: There is a thorough discussion of medication non-adherence issues and a few adherence-improving methods.
Conclusion: Adherence to treatment guidelines is essential in the treatment of any disease.
Keywords: medication non-adherence, patient non-compliance, avoidable medical costs, low health literacy, vaccine negligence.
Reference
1. Grissinger M. The Five Rights: A Destination without a Map. Physical Therapy-Oxford Academic. 2010;35(10):542.
2. Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clinic Proceedings. 2011;86(4):304-314. doi: 10.4065/mcp.2010.0575.
3. Center for Drug Evaluation and Research. Why you need to take your medications as prescribed or instructed. U.S. Food and Drug Administration. https://www.fda.gov/drugs/special-features/why-you-need-take-your-medications-prescribed-or-instructed. Accessed November 5, 2022.
4. Barnett NL. Medication adherence: where are we now? A UK perspective. European Journal of Hospital Pharmacy: Science and Practice 2014;21:181-184. https://doi.org/10.1136/ejhpharm-2013-000373
5. Record 6.8M people waiting for hospital treatment in England. The Guardian. http://www.theguardian.com/society/2022/sep/08/waiting-lists-for-routine-hospital-treatment-in-england-break-record. Published September 8, 2022.
6. Andrews L. 60% of NHS patients have waited 18 weeks for treatment at worst-performing hospital trust. Daily Mail Online. http://www.dailymail.co.uk/news/article-10577387/60-NHS-patients-waited-18-weeks-treatment-worst-performing-hospital-trust.html. Published March 7, 2022.
7. Mohiuddin, A. K. “Chapter 14. Patient Compliance”. The Role of the Pharmacist in Patient Care: Achieving High Quality, Cost-Effective and Accessible Healthcare Through a Team-Based, Patient-Centered Approach, Universal-Publishers, 2020, pp. 250-270.
https://www.universal-publishers.com/book.php?method=ISBN&book=1627343083
8. Cutler RL, Torres-Robles A, Wiecek E, et al. Pharmacist-led medication non-adherence intervention: reducing the economic burden placed on the Australian health care system. Patient Preference and Adherence (Dove Medical Press). 2019;13:853-862. Published 2019 May 23. doi:10.2147/PPA.S191482
9. Lim R, Ellett LM, Semple S, Roughead EE. The extent of medication-related hospital admissions in Australia: A review from 1988 to 2021. Drug Safety. 2022;45(3):249-257. doi:10.1007/s40264-021-01144-1.
10. Wolters Kluwer. Medication nonadherence: Medicine's weakest link (Medication Nonadherence Infographic). https://www.wolterskluwer.com/en/expert-insights/medication-nonadherence-medicines-weakest-link. Published 2020. Accessed February 11, 2023.
11. Kardas P, Bago M, Barnestein-Fonseca P, et al. Reimbursed medication adherence enhancing interventions in 12 European countries: Current state of the art and future challenges. Frontiers in Pharmacology. 2022;13:944829. Published 2022 Aug 11. doi:10.3389/fphar.2022.944829
12. van Boven JF, Tsiligianni I, Poto?njak I, Mihajlovi? J, Dima AL, NabergojMakovec U, Ágh T, Kardas P, Ghiciuc CM, Petrova G, Bitterman N, Kamberi F, Culig J, Wettermark B. European Network to Advance Best Practices and Technology on Medication Adherence: Mission Statement. Frontiers in Pharmacology. 2021 Oct 11;12:748702. doi: 10.3389/fphar.2021.748702.
13. Bonsu KO, Young S, Lee T, Nguyen H, Chitsike RS. Adherence to Antithrombotic Therapy for Patients Attending a Multidisciplinary Thrombosis Service in Canada - A Cross-Sectional Survey. Patient Preference and Adherence (Dove Medical Press). 2022 Jul 26;16:1771-1780. doi: 10.2147/PPA.S367105.
14. Zhang Y, Flory JH, Bao Y. Chronic Medication Nonadherence and Potentially Preventable Healthcare Utilization and Spending Among Medicare Patients. Journal of General Internal Medicine. 2022 Nov;37(14):3645-3652. doi: 10.1007/s11606-021-07334-y.
15. Bulik BS. Nonadherence costs pharma $600B-plus in annual sales: Study. Fierce Pharma. https://www.fiercepharma.com/marketing/non-adherence-costs-healthcare-system-patient-outcomes-and-pharma-bottom-line. Published November 22, 2016. Accessed November 24, 2022.
16. Bahta M, Tesfamariam S, Weldemariam DG, Yemane H, Tesfamariam EH, Alem T, Russom M. Dispensing of antibiotics without prescription and associated factors in drug retail outlets of Eritrea: A simulated client method. PLoS One. 2020 Jan 24;15(1):e0228013. doi: 10.1371/journal.pone.0228013.
17. Improve antibiotic use. Centers for Disease Control and Prevention. https://www.cdc.gov/sixeighteen/hai/index.htm. Published March 9, 2022. Accessed November 18, 2022.
18. Antimicrobial Resistance Collaborators. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022 Feb 12;399(10325):629-655. doi: 10.1016/S0140-6736(21)02724-0.
19. Rawson TM, Moore LSP, Zhu N, et al. Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing. Clinical Infectious Diseases-Oxford Academic. 2020;71(9):2459-2468. doi:10.1093/cid/ciaa530.
20. Clancy CJ, Nguyen MH. Coronavirus disease 2019, superinfections, and antimicrobial development: what can we expect? Clinical Infectious Diseases-Oxford Academic. 2020;71:2736-2743
21. Daria S, Islam MR. Indiscriminate Use of Antibiotics for COVID-19 Treatment in South Asian Countries is a Threat for Future Pandemics Due to Antibiotic Resistance. Clinical Pathology - SAGE Journals. 2022;15:2632010X221099889. Published 2022 May 18. doi:10.1177/2632010X221099889
22. Langford B.J., So M., Raybardhan S., Leung V., Soucy J.R., Westwood D., Daneman N., MacFadden D.R. Antibiotic prescribing in patients with COVID-19: Rapid review and meta-analysis. Clinical Microbiology and Infection. 2021;27:520–531. doi: 10.1016/j.cmi.2020.12.018.
23. Cong W, Poudel AN, Alhusein N, Wang H, Yao G, Lambert H. Antimicrobial Use in COVID-19 Patients in the First Phase of the SARS-CoV-2 Pandemic: A Scoping Review. Antibiotics (Basel). 2021;10(6):745. Published 2021 Jun 19. doi:10.3390/antibiotics10060745.
24. Kamara IF, Kumar AMV, Maruta A, et al. Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020-2021: Practice Does Not Follow Policy. International Journal of Environmental Research and Public Health. 2022;19(7):4005. Published 2022 Mar 28. doi:10.3390/ijerph19074005
25. Usman M, Farooq M, Hanna K. Environmental side effects of the injudicious use of antimicrobials in the era of COVID-19. Science of The Total Environment. 2020;745:141053. doi: 10.1016/j.scitotenv.2020.141053.
26. Kasciuškevi?i?t? S, Gumbrevi?ius G, Vendzelyt? A, Š?iupokas A, Petrikonis K, Kaduševi?ius E. Impact of the World Health Organization Pain Treatment Guidelines and the European Medicines Agency Safety Recommendations on Nonsteroidal Anti-Inflammatory Drug Use in Lithuania: An Observational Study. Medicina (Kaunas, Lithuania). 2018;54(2):30. Published 2018 May 11. doi:10.3390/medicina54020030.
27. Davis A, Robson J. The dangers of NSAIDs: look both ways. British Journal of General Practice. 2016;66(645):172-173. doi:10.3399/bjgp16X684433.
28. Lucas GNC, Leitão ACC, Alencar RL, Xavier RMF, Daher EF, Silva Junior GBD. Pathophysiological aspects of nephropathy caused by non-steroidal anti-inflammatory drugs. Brazilian Journal of Nephrology (BJN) 2019 Jan-Mar;41(1):124-130. doi: 10.1590/2175-8239-JBN-2018-0107.
29. Mohiuddin AK. Medication adherence: Fact or fictions? Current Research in Public Health. 2022;2(1):18-21. doi:10.31586/crph.2022.533
30. Jahrami H, BaHammam AS, Bragazzi NL, Saif Z, Faris M, Vitiello MV. Sleep problems during the COVID-19 pandemic by population: a systematic review and meta-analysis. Journal of Clinical Sleep Medicine. 2021 Feb 1;17(2):299-313. doi: 10.5664/jcsm.8930.
31. Ostuzzi G, Papola D, Gastaldon C, Schoretsanitis G, Bertolini F, Amaddeo F, Cuomo A, Emsley R, Fagiolini A, Imperadore G, Kishimoto T, Michencigh G, Nosé M, Purgato M, Dursun S, Stubbs B, Taylor D, Thornicroft G, Ward PB, Hiemke C, Correll CU, Barbui C. Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations. BMC Medicine-Springer Nature. 2020 Jul 15;18(1):215. doi: 10.1186/s12916-020-01685-9.
32. Sarangi A, McMahon T, Gude J. Benzodiazepine Misuse: An Epidemic within a Pandemic. Cureus. 2021;13(6):e15816. Published 2021 Jun 21. doi:10.7759/cureus.15816
33. Bhadelia A, De Lima L, Arreola-Ornelas H, Kwete XJ, Rodriguez NM, Knaul FM. Solving the Global Crisis in Access to Pain Relief: Lessons From Country Actions. American Journal of Public Health. 2019 Jan;109(1):58-60. doi: 10.2105/AJPH.2018.304769
34. Lopez G. Marijuana Majority/ Americans support marijuana legalization, but many of their political leaders do not. The New York Times. https://www.nytimes.com/2022/11/23/briefing/legal-weed-marijuana.html. Published November 23, 2022.
35. OltermannP. Germany announces plan to legalise cannabis for recreational use. The Guardian. https://www.theguardian.com/world/2022/oct/26/germany-to-legalise-cannabis-for-recreational-use. Published October 26, 2022.
36. Mohiuddin AK. Our low health literacy needs urgent fixing.https://www.thedailystar.net/opinion/views/news/our-low-health-literacy-needs-urgent-fixing-3193246. Published December 11, 2022.
37. Alam MM, Melhim LKB, Ahmad MT, Jemmali M. Public Attitude Towards COVID-19 Vaccination: Validation of COVID-Vaccination Attitude Scale (C-VAS). Journal of Multidisciplinary Healthcare - Dove Medical Press. 2022;15:941-954. Published 2022 Apr 29. doi:10.2147/JMDH.S353594
38. Danabal KGM, Magesh SS, Saravanan S, Gopichandran V. Attitude towards COVID 19 vaccines and vaccine hesitancy in urban and rural communities in Tamil Nadu, India - a community based survey. BMC Health Services Research. 2021;21(1):994. Published 2021 Sep 21. doi:10.1186/s12913-021-07037-4
39. Leelavathy M, Messaline S, Ramachandran D, Sukumaran A, Jose R, Noufel AN. Attitude towards COVID-19 vaccination among the public in Kerala: A cross sectional study. Journal of Family Medicine and Primary Care. 2021;10(11):4147-4152. doi:10.4103/jfmpc.jfmpc_583_21
40. Paul E, Steptoe A, Fancourt D. Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications. The Lancet Regional Health - Europe. 2021;1:100012. doi:10.1016/j.lanepe.2020.100012
41. Chauke GD, Nakwafila O, Chibi B, Sartorius B, Mashamba-Thompson T. Factors influencing poor medication adherence amongst patients with chronic disease in low-and-middle-income countries: A systematic scoping review. Heliyon. 2022 Jun 15;8(6):e09716. doi: 10.1016/j.heliyon.2022.e09716.
42. Chong E, Wang H, King-Shier KM, Quan H, Rabi DM, Khan NA. Prescribing patterns and adherence to medication among South-Asian, Chinese and white people with type 2 diabetes mellitus: a population-based cohort study. Diabetic Medicine. 2014;31(12):1586-1593. doi:10.1111/dme.12559
43. Sohal T, Sohal P, King-Shier KM, Khan NA. Barriers and Facilitators for Type-2 Diabetes Management in South Asians: A Systematic Review. PLoS One. 2015 Sep 18;10(9):e0136202. doi: 10.1371/journal.pone.0136202.
44. Alsairafi ZK, Taylor KM, Smith FJ, Alattar AT. Patients' management of type 2 diabetes in Middle Eastern countries: review of studies. Patient Preference and Adherence (Dove Medical Press). 2016 Jun 10; 10:1051-62. doi: 10.2147/PPA.S104335.
45. Almigbal TH, Almutairi KM, Vinluan JM, et al. Association of health literacy and self-management practices and psychological factor among patients with type 2 diabetes mellitus in Saudi Arabia. Saudi Medical Journal. 2019;40(11):1158-1166. doi:10.15537/smj.2019.11.24585
46. Nair SC, Sreedharan J, Satish KP, Ibrahim H. Health literacy in a high income Arab country: A nation-wide cross-sectional survey study. PLoS One. 2022;17(10):e0275579. Published 2022 Oct 5. doi:10.1371/journal.pone.0275579
47. Hashim SA, Barakatun-Nisak MY, Abu Saad H, Ismail S, Hamdy O, Mansour AA. Association of Health Literacy and Nutritional Status Assessment with Glycemic Control in Adults with Type 2 Diabetes Mellitus. Nutrients (MDPI). 2020;12(10):3152. Published 2020 Oct 15. doi:10.3390/nu12103152
48. Hussein SH, Albatineh AN, Almajran A, Ziyab AH. Association of health literacy and other risk factors with glycemic control among patients with type 2 diabetes in Kuwait: A cross-sectional study. Primary Care Diabetes. 2021;15(3):571-577. doi:10.1016/j.pcd.2021.01.011
49. Khatiwada B, Rajbhandari B, Mistry SK, Parsekar S, Yadav UN. Prevalence of and factors associated with health literacy among people with Noncommunicable Diseases (NCDs) in South Asian countries: A systematic review. Clinical Epidemiology and Global Health. 2022;18:101174. doi:10.1016/j.cegh.2022.101174.
50. Rajah R, Hassali MAA, Murugiah MK. A systematic review of the prevalence of limited health literacy in Southeast Asian countries. Public Health (Elsevier). 2019;167:8-15. doi:10.1016/j.puhe.2018.09.028.
51. Saleh A, Wirda W, Irwan AM, Latif AI. The relationships among self-efficacy, health literacy, self-care and glycemic control in older people with type 2 diabetes mellitus. Working with Older People. 2021;25(2):164-169. doi:10.1108/wwop-08-2020-0044.
52. Choudhry NK, Kronish IM, Vongpatanasin W, et al. Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association. Hypertension. 2022;79(1):e1-e14. doi:10.1161/HYP.0000000000000203.
53. Elnaem MH, Mosaad M, Abdelaziz DH, et al. Disparities in Prevalence and Barriers to Hypertension Control: A Systematic Review. International Journal of Environmental Research and Public Health. 2022;19(21):14571. Published 2022 Nov 6. doi:10.3390/ijerph192114571
54. Keasley J, Oyebode O, Shantikumar S, et al. A systematic review of the burden of hypertension, access to services and patient views of hypertension in humanitarian crisis settings. BMJ Glob Health. 2020;5(11):e002440. doi:10.1136/bmjgh-2020-002440
55. Alawneh IS, Yasin A, Musmar S. The Prevalence of Uncontrolled Hypertension among Patients Taking Antihypertensive Medications and the Associated Risk Factors in North Palestine: A Cross-Sectional Study. Advances in Medicine. 2022; 2022:5319756. Published 2022 Aug 25. doi:10.1155/2022/5319756
56. Rahman A, Biswas J, Banik PC. Non-communicable diseases risk factors among the forcefully displaced Rohingya population in Bangladesh. PLOS Global Public Health. 2022;2(9). doi:10.1371/journal.pgph.0000930
57. Lossius MI, Alfstad KÅ, Aaberg KM, Nakken KO. Discontinuation of antiepileptic drugs in seizure-free patients - when and how?.Seponeringavantiepileptikavedanfallsfrihet – nåroghvordan?. Journal of the Norwegian Medical Association. 2017;137(6):451-454. Published 2017 Mar 21. doi:10.4045/tidsskr.16.0957
58. Caqueo-Urízar A, Urzúa A, Mena-Chamorro P, Bravo de la Fuente J. Effects of Adherence to Pharmacological Treatment on the Recovery of Patients with Schizophrenia. Healthcare (Basel). 2021;9(9):1230. Published 2021 Sep 18. doi:10.3390/healthcare9091230.
59. Banerjee S, Varma RP. Factors affecting non-adherence among patients diagnosed with unipolar depression in a psychiatric department of a tertiary hospital in Kolkata, India. Depression Research and Treatment (Hindawi). 2013;2013:809542.
60. Graeupner D, Coman A. The dark side of meaning-making:How social exclusion leads to superstitious thinking. Journal of Experimental Social Psychology. 2017;69:218–22.
61. Puckree T, Mkhize M, Mgobhozi Z, Lin J. African traditional healers: what health care professionals need to know. International Journal of Rehabilitation Research. 2002;25(4):247-251. doi:10.1097/00004356-200212000-00001.
62. Taher M, Pashaeypoor S, Cheraghi MA, Karimy M, Hoseini ASS. Superstition in health beliefs: Concept exploration and development. Journal of Family Medicine and Primary Care. 2020;9(3):1325-1330. Published 2020 Mar 26. doi:10.4103/jfmpc.jfmpc_871_19
63. Grim BJ, Grim ME. Belief, Behavior, and Belonging: How Faith is Indispensable in Preventing and Recovering from Substance Abuse. Journal of Religion and Health (Springer). 2019;58(5):1713-1750. doi:10.1007/s10943-019-00876-w
64. Mirahmadizadeh A, Delam H, Seif M, Banihashemi SA, Tabatabaee H. Factors Affecting Insulin Compliance in Patients with Type 2 Diabetes in South Iran, 2017: We Are Faced with Insulin Phobia. Iranian Journal of Medical Sciences. 2019;44(3):204-213.
65. Félix IB, Henriques A. Medication adherence and related determinants in older people with multimorbidity: a cross?sectional study. Nursing Forum (Wiley Online Library). 2021;56:834–843. doi:10.1111/nuf.12619
66. Chippa V, Roy K. Geriatric Cognitive Decline and Polypharmacy. National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK574575/. Published January 2022. Accessed November 18, 2022.
67. Varghese D, Ishida C, Koya HH. Polypharmacy. National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK532953/. Published January 2022. Accessed November 18, 2022.
68. Santer M, Ring N, Yardley L, Geraghty AW, Wyke S. Treatment non-adherence in pediatric long-term medical conditions: systematic review and synthesis of qualitative studies of caregivers' views. BMC Pediatrics. 2014;14:63. Published 2014 Mar 4. doi:10.1186/1471-2431-14-63
69. Al-Hassany L, Kloosterboer SM, Dierckx B, Koch BC. Assessing methods of measuring medication adherence in chronically ill children-a narrative review. Patient Preference and Adherence (Dove Medical Press). 2019;13:1175-1189. Published 2019 Jul 22. doi:10.2147/PPA.S200058
70. Wu YY, Luo YY, Huang LF, et al. ZhonghuaErKeZaZhi (Chinese journal of pediatrics - Scimago). 2022;60(11):1191-1195. doi:10.3760/cma.j.cn112140-20220110-00036
71. Jin J, Sklar GE, Min Sen Oh V, Chuen Li S. Factors affecting therapeutic compliance: A review from the patient's perspective. Therapeutics and Clinical Risk Management (Dove Press). 2008 Feb;4(1):269-86. doi: 10.2147/tcrm.s1458.
72. Wilder ME, Kulie P, Jensen C, et al. The Impact of Social Determinants of Health on Medication Adherence: a Systematic Review and Meta-analysis. Journal of General Internal Medicine (Springer). 2021;36(5):1359-1370. doi:10.1007/s11606-020-06447-0
73. Kardas P, Lewek P, Matyjaszczyk M. Determinants of patient adherence: a review of systematic reviews. Frontiers in Pharmacology. 2013;4:91. Published 2013 Jul 25. doi:10.3389/fphar.2013.00091
74. Bosworth HB, Blalock DV, Hoyle RH, Czajkowski SM, Voils CI. The role of psychological science in efforts to improve cardiovascular medication adherence. American Psychologist (by American Psychological Association). 2018;73(8):968-980. doi:10.1037/amp0000316
75. Correia S, Correia A, Videira I, et al. Health gains of telephone follow-up nursing intervention to patient with heart disease. Gerontechnology. 2019:107-113. doi:10.1007/978-3-030-16028-9_10
76. Tan CS. The Need of Patient Education to Improve Medication Adherence Among Hypertensive Patients. Malaysian Journal of Pharmacy. 2020;6(1):1-5. doi:10.52494/moel1486
77. Michie S, Richardson M, Johnston M, et al. The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions. Annals of Behavioral Medicine (Oxford Academic). 2013;46(1):81-95. doi:10.1007/s12160-013-9486-6
78. Howren MB, Gonzalez JS. Treatment adherence and illness self-management: introduction to the special issue. Journal of Behavioral Medicine (Springer). 2016;39(6):931-934. doi:10.1007/s10865-016-9804-0
79. Bahri P, Harrison-Woolrych M. Focusing on risk communication about medicines: why now?. Drug Safety (Springer). 2012; 35(11):971-975. doi:10.1007/BF03261984
80. Fukuda Y, Ando S, Saito M. Risk awareness, medication adherence, and driving behavior as determined by the provision of drug information to patients. Patient Education and Counselling. 2020; 103(8):1574-1580. doi:10.1016/j.pec.2020.02.037