Albert Science International Organization

Abstract

Nanoscience and nanotechnology are the study and application of extremely small things and can be used across all the other science fields, such as chemistry, biology, physics, material science, and engineering. Nanotechnology is the engineering of functional systems at the molecular scale and this covers both current work and concepts that are more advanced.  Nanotechnology involves the creation and use of materials and devices at the level of molecules and atoms. Nanotechnology offers important new tools expected to have a great impact on many areas in medical technology. It provides extraordinary opportunities not only to improve materials and medical devices but also to create new “smart” devices and technologies where existing and more conventional technologies may be reaching their limits. It is expected to accelerate scientific as well as economic activities in medical research and development. Nanotechnology has the potential to make significant contributions to disease detection, diagnosis, therapy, and prevention. Tools are an important and integral part for early detection. Several medical devices have already been benefited from recent developments in nanotechnology. These medical devices are in use or are currently being commercialized. Nanotechnology is definitely a medical boon for diagnosis, treatment and prevention of cancer disease. Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Nanomedicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future. The applications for nanomedicine like Biopharmaceutical Application, Implantable Material and Devices, Surgical aids, Diagnostic tools have been illustrated.

Keywords: Biopharmaceutical Application, Implantable Material and Devices, Surgical aids.

1.     Zsigmondy, R. Colloids and the Ultramicroscope, J. Wiley and Sons, NY, Lyklema, J., Fundamentals   of Interface and Colloid Science, vol.1-5 Academic Press.

2.     De Jong WH, Borm PJA. Drug delivery and nanoparticles: Applications and hazards. International Journal of Nanomedicine 2008; 3(2): 133-149.

3.     Naik, A.B. and Selukar, N.B., Role of nanotechnology in medicine, Everyman’s Science, 2009; XLIV (3), 151-15.

4.     Silva GA. Introduction to Nanotechnology and Its Applications to Medicine. Surgical Neurology 2004; 61(3): 216-220.

5.     http://www.oecd.org/about/0,.html.

6.     http://www.oecd.org/dataoecd.

7.     Iijima, Sumio, Helical microtubules of graphitic carbon. Nature. 1991; 354 (6348): 56–58.

8.    Petros RA, DeSimone JM. Strategies in the design of nanoparticles for therapeutic ap? plications. Nature Reviews Drug Discovery 2010; 9(8): 615-627.

9.     Ghosh P, Han G, De M, Kim CK, Rotello VM. Gold nanoparticles in delivery applica? tions. Advanced Drug Delivery Reviews 2008; 60(11): 1307-1315

10.  Pathak Y, Thassu D. Drug Delivery Nanoparticles Formulation and Characterization. Rijeka: PharmaceuTech Inc.; 2009. p1-393.

11.  Ruoslahti E, Bhatia SN, Sailor MJ. Targeting of drugs and nanoparticles to tumors. Journal of Cell Biology 2010; 188(6): 759-768.

12.  Jain, K.K. The role of nanobiotechnology in drug discovery. Drug Discovery Today (2005)10(21).1435- 1442.

13. Vasir, J. K. Reddy M.K. and Labhasetwar V. D. Nanosystems in Drug Targeting: Opportunities and Challenges. Current Nanoscience. (2005), 1, 47-64.

14.  Xie J, Lee S, Chen X. Nanoparticle-based theranostic agents. Advanced Drug Deliv? ery Reviews, 2010; 62(11): 1064-1079.

15.  Wang K, Wu X, Wang J, Huang J. Cancer stem cell theory: therapeutic implications for nanomedicine. International Journal of Nanomedicine 2013; 8(1): 899-908.

16.  C. Mao, W. Sun & N. C. Seeman, Assembly of Borromean rings from DNA,1997;  Nature 386(6621): 137–138.

17.  Kubik, T. Bogunia-Kubik K., Sugisaka. M. Nanotechnology on Duty in Medical Applications. Current Pharmaceutical Biotechnology. 2005; 6, 17-33.

18.  Richard Zare Stanford, http://www.stanford.edu/group/Zarelab

19.  Baba R. Patent and Nanomedicine. Nanomedicine, 2007; 2(3), 351-374.

20.  Chen YS, Hung YC, Liau I, Huang GS. Assessment of the In Vivo Toxicity of Gold Nanoparticles. Nanoscale Research Letters, 2009; 4(8): 858-864.

21.  Chen YS, Hung YC, Liau I, Huang GS. Assessment of the In Vivo Toxicity of Gold Nanoparticles. Nanoscale Research Letters, 2009 ;4(8): 858-864.

22.  Adam Arkin UC Berkeley, http://www. stanford.edu/group/blocklab/

23.  Dan Branton Harvard, http://mcb.harvard.edu/ Faculty /Branton.html

24.  http://www.mayo.edu/bir/Projects/ MoleculeVis /MolecularVis.html

25.  http://www.bio.ornl.gov/gst/staff/greenbaum. html

26.  Shuming Nie Emory http://www.emory.edu/ CHEMISTRY/ faculty/nie.html

27.  Klaus Schulten U Illinois Urbana-Cham.

28. http://www.ks.uiuc.edu/Overview/KS/schulten.html

29.  Lydia Sohn Princeton http://www.poem. princeton.edu/Bios/Sohn.htm

30.  Johnathan Sweedler U Illinois Urbana-Cham. http://mrel.beckman.uiuc.edu/sweedler/

31.  http://www.cytokinetics.com/cyto/sm_trautman

32.  David Walt Tufts, http://www.chem.tufts.edu /faculty/walt/

33.  Sunney Xie Harvard, http://bernstein.harvard.edu /pages/AboutProfXie.html

34. Richard Zare Stanford, http://www.stanford.edu/group/Zarelab/

35.  Nahar M, Dutta T, Murugesan S, Asthana A, Mishra D, Rajkumar V, Tare M, Saraf S, Jain NK. Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives. Crit Rev Ther Drug Carrier Syst, 2006; 23(4): 259-318.

36.  James Collins Boston U, http://bme.bu.edu/ faculty/collins.html