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BOOK DETAILS:


Toxicological and Therapeutic aspects of Nanoparticles
 by Dr. Rama Narsimha Reddy Anreddy, Dr. Srividya Lonkala & Dr. Mahendar Porika


ISBN

:

 978-93-5281-167-0

Name

:

Toxicological and Therapeutic aspects of Nanoparticles

Price

:

100 INR/ 5 USD 

Edition

:

1st

Author/s

:

Dr. Rama Narsimha Reddy Anreddy, Dr. Srividya Lonkala & Dr. Mahendar Porika

Type

:

Text Book

Pages

:

100

Year of Publication

:

2017

Publisher

:

ASIO

Format &Stock Status

:

e-Book available

doi no. : http://doi-ds.org/doilink/08.2017-87949256/
Language : English

 


CONTENTS


S.No

Contents

1

Nanoparticles-Introduction

2

Physicochemical Characteristics as Determinants of Biological Activity

3

Nanoparticles exposure- in occupational settings

4

Portals for entry of Nanoparticles

5

Biokinetics- The Respiratory Tract

6

ROS Mechanisms of Nano-sized Particle Toxicity

7

Pathogenic processes- health effects

8

Scientific evidences for toxicity

9

Significance of ZnO Nanoparticles

10

Nanoparticles as Antimicrobial agents

11

Antimicrobial mechanism of nanoparticles

12

References

 


Authors Information:


Dr. Rama Narsimha Reddy Anreddy is working as Professor of Pharmacy at Jyothishmathi Institute of Pharmaceutical Sciences, Karimnagar, Telangana State and having vast experience in nanoparticles toxicological aspects. He has published morethan 70 research publications in various impact factor, peer reviewed national and international journals. He has published seven books/chapters with various publishers. He has contributed a lot to the scientific research in the field of nanotechnology.

Dr. Srividya Lonkala is working as Associate Professor of Pharmacy at Jyothishmathi Institute of Pharmaceutical Sciences, Karimnagar, Telangana State and she has published morethan 10 research publications in various peer reviewed national and international journals. She is focused her research to synthesize novel compounds for treatment of cancer and diabetes.

Dr. Mahendar Porika is working as Lecturer, Department of Biotechnology, Kakatiya University, Warangal, Telangana State and having vast experience in nanoparticles research. He has published morethan 50 research publications in various impact factor, peer reviewed national and international journals. He has published many more books/chapters with various publishers. He has contributed a lot to the scientific research in the field of nanotechnology.


Salient Features:


Background

Nanotechnology involves the creation and manipulation of materials at nanoscale levels to create products that exhibit novel properties. Engineered nanomaterials, or nanoparticles (NP), are defined as materials produced within the range of 1-100 nm (10-9m) in length or diameter. Nanomaterials possess increased structural integrity as well as unique mechanical, optical, chemical, electrical and magnetic properties (Oberdorster et al., 2005; Thomas and Sayre, 2005). In this nanotechnological development, nanoparticles have attracted a great deal of attention. The unique function of these “nanomaterials” directly depends on their size and structure-dependent properties, as do the environmental and health effects. Nanoparticles are of particular concern due to their extremely high surface area and increased reactivity. Because of these unique physical and chemical properties, NP can potentially impact the health of those exposed to them during industrial manufacturing and production. Nanomaterials have gained enormous attention and are currently being widely used in modern technology. Although the applications and benefits of these engineered nanomaterials are extensively studied, (Hoet et al., 2004) there is a severe lack of information concerning the human health and environmental implications of occupational exposure during the manufacturing and handling process. Therefore, in the present book we have reviwed the potential toxic effects of nanoparticles by exploring the therapeutic like antimicrobial aspects.


Summary  

In this book, we have focused on the toxicological and therapeutic aspects of nanoparticles. As the applications and usage of nanosized particles are increasing enormously in day to day technology, this book will explore the newer aspects of nanoparticles. Nanotechnology involves the creation and manipulation of materials at nanoscale levels to create products that exhibit novel properties. Engineered nanomaterials, or nanoparticles (NP), are defined as materials produced within the range of 1-100 nm (10-9m) in length or diameter. Nanomaterials possess increased structural integrity as well as unique mechanical, optical, chemical, electrical and magnetic properties. In this nanotechnological development, nanoparticles have attracted a great deal of attention. The unique function of these “nanomaterials” directly depends on their size and structure-dependent properties, as do the environmental and health effects. Nanoparticles are of particular concern due to their extremely high surface area and increased reactivity. Because of these unique physical and chemical properties, NP can potentially impact the health of those exposed to them during industrial manufacturing and production. Nanomaterials have gained enormous attention and are currently being widely used in modern technology. Although the applications and benefits of these engineered nanomaterials are extensively studied, there is a severe lack of information concerning the human health and environmental implications of occupational exposure during the manufacturing and handling process. Therefore, in the present book we have reviewed the potential toxic effects of nanoparticles by exploring the therapeutic like antimicrobial aspects.