Tamal Maity, Sounik Banerjee, Amlan Bishal, Rupajit Bhattacharjee, Satya Prasanna Das. The Diagnosis and Management of Pre-Eclampsia and Eclampsia: A Review, ASIO Journal of Pharmaceutical & Herbal Medicines Research (ASIO-JPHMR), 2016: 2(1), 21-23.
ARTICLE TYPE: Review
dids/doi No.: 12.2015-77737978
dids link: http://dids.info/didslink/02.2016-14516413/
The accurate cause of pre-eclampsia is not implicit. Often there are no symptoms and it may be picked up at your routine antenatal appointments when you have your blood pressure checked and urine tested. This is why you are asked to bring a urine sample to your appointments. Other important factors are the severity of the mother’s preeclampsia, whether or not it recurred, and a history of low birth weight babies. This does not mean the person will definitely develop these heart problems if he/she had preeclampsia, but for some women pregnancy can be considered a “failed stress test”, possibly unmasking other health issues. Many of the risk factors for preeclampsia and diseases affecting your blood pressure and heart are the same. They include a family history of high blood pressure, heart disease and diabetes, being overweight, problems with blood clotting, and metabolic syndrome. If there is no initial response to oral therapy or if it cannot be tolerated, control should be by repeated boluses of labetalol 50mg followed by a labetalol infusion as a first line drug. The use of a second line agent (hydralazine or nifedipine) can cause precipitate drops in blood pressure, particularly if magnesium sulphate therapy is also being administered.
Keywords: Pre-eclampsia, blood pressure, maternal and perinatal mortality, labetalol, hydralazine, nifedipine.
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