Tanvi N. Sakhare1 , Prajakta N. Dongare*1, Prerna P. Patinge, Manisha P. More1, Anuja S. Motule, Ravindra L. Bakal1, Harigopal S. Sawarkar2
1IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Mardi road, Amravati-444 602, MS, India.
2IBSS’s Dr. Rajendra Gode College of Pharmacy, Mardi road, Amravati-444 602, MS, India.
ARTICLE TYPE: REVIEW
DOI : 10.2016-19146535/ ; DOI Link :: https://doi-ds.org/doilink/07.2021-25628878/ASIO JPHMR/ 10.2016-19146535/V7/I2/458
Abstract:
Phytoconstituents are chemical compounds that occur naturally in plants. Some are responsible for colour and other organoleptic properties. The term is generally refer to biologically significant chemicals, but not established as essential nutrients. A wide range of technologies is available for the extraction of active components and essential oils from medicinal and aromatic plants. The choice depends on the economic feasibility and suitability of the process to the particular situation. Extraction is the first crucial step in preparation of plant formulations. Modern methods of extraction are effective in advancing the development of traditional herbal remedies. The development of modern sample-preparation techniques with significant advantages over conventional methods for the extraction and analysis of medicinal plants is likely to play an important role in the overall effort of ensuring availability of high-quality herbal products to consumers worldwide. In this article principle behind operation of various extraction methods, factors influencing method performance, research progress, strength and weakness of different extraction approaches are discussed. Emphasis is put on the methods which are solvent and energy saving, and suitable for thermolabile phytocompounds. The various processes of production of medicinal plant extracts and essential oils are reviewed in this paper.
Keywords: Extraction Efficiency, Microwave Assisted Extraction (MAE), Supercritical Fluid Extraction (SFE), Ultrasonication Assisted Extraction (UAE).
1. P. Tonthubthimthong S. Chuaprasert, P. Douglas and W. Luewisutthichat. Supercritical CO2 extraction of nimbin from neem seeds an experimental study, Journal of Food Engineering. (2011),47 (4), pp. 289-293.
2. Venugopal R, Liu RH Phytochemicals in diets for breast cancer prevention: The importance of resveratrol and ursolic acid. Food Sci Hum Wellness, (2012), 1: 1-13.
3. Willcox BJ, Willcox DC, Todoriki H, Fujiyoshi A, Yano K, et al. Caloric restriction, the traditional okinawan diet, and healthy aging: The diet of the world’s longest-lived people and its potential impact on morbidity and life span. Ann. N. Y. Acad. Sci, (2007), 114: 434-455.
4. Willcox DC, Willcox BJ, Todoriki H, Suzuki M. The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load. J Am CollNutr, (2009), 28: 500S-516S.
5. Mukherjee PK, Maity N, Nema NK, Sarkar BK. Bioactive compounds from natural resources against skin aging. Phytomedicine, (2011), 19: 64- 73.
6. Chemistry LibreTexts. 2017-10-05. Retrieved 2019-11-10.
7. Ramalakshmi, K.; Raghavan, B. "Caffeine in Coffee: Its Removal. Why and How?". Critical Reviews in Food Science and Nutrition. (1999), 39 (5): 441–456.
8. Ray Sahelian, M.D. Phenolic Compounds and Acids, benefit of phenols. (January 20, 2016).
9. Karin Fester. Plant Alkaloids Leipzig, Germany. Published online. .(March 2010).
10. The Columbia Encyclopedia. Alkaloid, 6th ed. The Columbia University Press. (2015).
11. http://www.phytochemicals.info/
12. Manpreet Kaur: Glycoside in Plant: Isolation and Types of Glycoside in Plant Photochemical Screening. (2015).
13. SameenaBano: Chemistry Of Natural Products Terpenoids Department of Chemistry Faculty of Science JamiaHamdard New Delhi-110062.
14. Nita Yadava, Rajesh Yadava , Anju GoyalbInt. J. Pharm. Sci. Rev. Res., (2014), 27(2), July – August; Article No. 45, Pages: 272-278.
15. https://en.wikipedia.org/wiki/Tannin
16. Shih-Chang Chien, Yueh-Chen Wu, Zeng-Weng Chen, and Wen-Chin Yang. Naturally Occurring Anthraquinones:Chemistry and Therapeutic Potential in Autoimmune Diabetes. Evidence-Based Complementary and Alternative Medicine, .(2015), Volume 2015 Article ID 357357, 13 pages.
17.www.wisegeek.com/what-are-plant-steroids.htm:What Are Plant Steroids?
18. https://en.wikipedia.org/wiki/Essential_oil.
19.A. Pandey, S. Tripathi. Concept of standardization, extraction and pre Phytochemical screening strategies for herbal drug.Journal of Pharmacognosy and Phytochemistry. (2014), 2 (5), pp. 115-119.
20.S. S. Handa, S.P.S. Khanuja, G. Longo and D.D. Rakesh, Extraction Technologies for Medicinal and Aromatic Plants, 1stedn , no. 66. United Nations Industrial Development Organization and the International Centre for Science and High Technology. Italy. (2008).
21.J. Azmir et al, Techniques for extraction of bioactive compounds from plant materials: A review. Journal of Food
Engineering.117, pp. 426–436.
22. M.G. Rasul. (2011 December). Extraction, Isolation and Characterization of Natural Products from Medicinal Plants.International Journal of Basic Sciences and Applied Computing. 2(6),pp. 1-6.
23. M. Bimakr et al. (2011, January). Comparison of different extraction methods for the extraction of major bioactive flavonoid compounds from spearmint (Menthaspicata L.) leaves. Food and Bioproducts processing. 89(1).
24. D. Grigonis, P. Sivik, M. Sandahl and C. Eskilsson. (2005, March). Comparison of different extraction techniques for isolation of antioxidants from sweet grass (Hierochloeodorata). Journal of Supercritical Fluids. 33 (15), pp. 223–233.
25. J. K. Parikh, M.A. Desai Hydrodistillation of Eseential Oil from Cymbopogonflexuosus. International Journal of Food Engineering, (2011), 7(1), 1-11.
26. Trusheva B, Trunkova D, Bankova V (2007) Different extraction methods of biologically active components from propolis: a preliminary study. Chem Cent J 13.
27. Kaufmann B and Christen P (2002), Recent extraction techniques for natural products: microwave-assisted extraction and pressurized solvent extraction. Phytochem. Anal 13: 105-113.
28. Handa SS, Khanuja SPS, Longo G, Rakesh DD (2008) Extraction Technologies for Medicinal and Aromatic Plants, (1stedn), no. 66. Italy: United Nations Industrial Development Organization and the International Centre for Science and High Technology.
29. Dhanani T, Shah S, Gajbhiye NA, Kumar S. Effect of extraction methods on yield, phytochemical constituents and antioxidant activity of Withaniasomnifera. Arab J Chem. (2013).
30. Methods Optimization in Accelerated Solvent Extraction in Technical note (2013) 208: 1-4.
31. Rahmalia W, Fabre JF, Mouloungui Z (2015) Effects of Cyclohexane/Acetone Ratio on Bixin Extraction Yield by Accelerated Solvent Extraction Method. Procedia Chem 14: 455-464.
32. Tan, Ji T,Jiang G, Hu F Simultaneous identification and quantification of five flavonoids in the seeds of Rheum palmatum L. by using accelerated solvent extraction and HPLC-PDA-ESI/MSn. Arab J Chem. (2014)
33. Patil, Sachin BS, Wakte PS, Shinde DB Optimization of supercriticalfluid extraction and HPLC identification of wedelolactone from Wedeliacalendulacea by orthogonal array design. (2013), J Adv Res 5: 629-635.
34. Naudé Y, De Beer WHJ, Jooste S, Van Der Merwe L, Van Rensburg SJ (1998) Comparison of supercritical fluid extraction and Soxhlet extraction for the determination of DDT, DDD and DDE in sediment. Water SA 24: 205-214.
35. M. Bimakr et al. (2011, January). Comparison of different extraction methods for the extraction of major bioactive flavonoid compounds from spearmint (Menthaspicata L.) leaves. Food and Bio products processing.89 (1), pp. 67-72.
36. S. Vidyadhar, M. Saidulu, T.K., Gopal, D.Chamundeeswari, U. Rao, D. Banji( 2010, December). In vitro anthelmintic activity of the whole plant of Enicostemmalittorale by using various extracts. International journal of applied biology and pharmaceutical technology. 1(3) 1119-1125.
37.W.Q.Zhang, G.L. Lin and C.W. Ye. Techniques for extraction and isolation of natural products: a comprehensive review. Chinese Medicine. (2018), 13(20), pp. 1-26.
38. Prajakta N. Dongare, Anuja S.Motule, Manisha P. More, Prerana A.Patinge, Ravindra Bakal. An Overview on Anticancer drugs from Marine source. World Journal of Pharmaceutical Research.2021; vol 10(1) : 950-956.
39. Motule AS, Nimbalwar MG, Panchale WA, ManwarJP, Bakal RL, Gudalwar BR. Development and physicochemical evaluation of bilayered transdermal patches of ondansetron hydrochloride. Journal of Innovation in Pharmaceutical and Biological Sciences. 2021; 8(3): 17-23.
40. Prajakta N. Dongare, Anuja S.Motule, Manisha P. More, Prerana A.Patinge, Ravindra Bakal. An Overview on Anticancer drugs from Marine source. World Journal of Pharmaceutical Research.2021; vol 10(1) : 950-956.
41. Gulhane CA, Motule AS, Atram SC, Mankar LM, Deshmukh DA, Bakal RL.An Overview On Nail Drug Delivery System: A Promising Application for Various diseases. European Journal of Biomedical and Pharmaceutical Sciences. 2021;8(2):104-110.